Endocrine Abstracts

Introduction: There are contradicting data about bone mineral density (BMD) in patients with type 2 diabetes mellitus (DM), although most studies describe increased BMD values in them. Due to this finding it is not clear how tightly bone fragility is bound with BMD in type 2 diabetic people.Design: We provided dual-energy X-ray absorptiometry of lumbar spine and proximal femur to 46 postmenopausal women with type 2 diabetes mellitus (DM), 14 of them had ...

Introduction: The diabetes mellitus (DM) is the known risk factor of fractures. The aim was to determine predictors of fractures in type 2 diabetic postmenopausal women without hyperparathyroidism.Design: We analyzed local trauma clinic data for 3 sequential years from 2 662 diabetic persons who were entered The National Register of diabetes mellitus patients (133 subjects with type 1 diabetes mellitus and 1995 ones with type 2 DM). Afterward we examined...

Background and aims: The aim was to determine psychoemotional state in diabetic and non-diabetic patients with or without fractures and its correlation with bone condition.Materials and methods: We examined 62 postmenopausal women with type 2 diabetes mellitus (DM), 29 of them had bone fracture within last month. The control group included 56 non-diabetic women, 26 within a group were recently fractured. Groups were comparable in body mass index, age, du...

A 21 years old man had growth failure since 11 y.o., micropenis, high-pitched voice, the absence of secondary sex characteristics and male sexual behavior, constant fatigue and weakness. The boy was born in time after 1st normal pregnancy, birth weight 3000 g, length 57 cm, had unilateral cryptorchidism (surgical treatment in 2002). At the age of 21 the height of the patient was 144 cm (SDS - 4.62), BMI 15 kg/m2 (BMI SDS −3.89), Tanner G1P1, bone age 13 y.o. I...

Introduction: Childhood cancer incidence increases all over the world, but it are optimistic that more than seventy percent of children with cancer survive due to radiation and chemotherapy. However cancer treatment may impair reproductive function. The aim of this study is to investigate level of pituitary hormones, testis/ovarian volume in women and men undergo cranial and craniospinal irradiation in childhood.Methods: Participators were examined with ...

Background and aims: The aim was to compare calcium homeostasis indexes in diabetic and non-diabetic patients with or without fractures.Materials and methods: We examined 62 postmenopausal women with type 2 diabetes mellitus (DM), 32 of them had bone fracture within last month. The control group included 54 non-diabetic women, 25 within a group were recently fractured. Groups were comparable in body mass index, age, duration of menopause and calcium inta...

Objective: To study if people with diabetes mellitus (DM) have increased risk of fracture.Methods: The study population consisted of 29 512 people aged 50 years or more. There were 1981 diabetic patients among them. The records of the local trauma clinic for two-year period were analyzed.Results: Women with DM had fewer fractures during two years than women without DM (relative risk 0.43; 95% confidence interval 0.30–0.61). Th...

Objective: To examine association between diabetes properties (type, duration, treatment regiment etc.) and risk of any fracture in diabetic population.Methods: We analyzed local trauma clinic data for 3 sequential years from 2662 diabetic persons who were entered The National Register of diabetes mellitus patients (133 subjects with type 1 diabetes mellitus (T1DM) and 1995 ones with T2DM).Results: Fracture risk was higher in T1DM ...